＜2024年＞

トピックス?その他

高岡 尚輝, ベストポスター賞を受賞して, 日本薬物動態学会 Newsletter,2024; 39(1).

受賞

■2024年7月　高岡 尚輝， ISSX/JSSX2024合同年会/若手研究者海外発表支援事業に採択（日本薬物動態学会）

■2024年7月　赤木 知裕，優秀講演賞（2024生態工学会年次大会）

■2024年2月　高岡 尚輝，篮球比分直播5年度学術論文奨励賞（和歌山県立医科大学）

＜2023年＞

原著論文

■Hanada H*, Morishita F, Sanoh S, Kashiwagi K, Kashiwagi A. Long-term Xenopus laevis tadpole -heart-organ-culture: Physiological changes in cholinergic and adrenergic sensitivities of tadpole heart with thyroxine-treatment. Current Research in Physiology. 2023;6: 100100.

■Ohtsuki Y, Sanoh S*, Yamao M, Kojima Y, Kotake Y, Tateno C*. Establishment of hyperoxic cell culture system for predicting drug-induced liver injury: reducing accumulated lipids in hepatocytes derived from chimeric mice with humanized liver.J Toxicol Sci. 2023;48(2):99-108.

■Ishida K, Takeda K, Takehara Y, Takabayashi T, Miyara M, Sanoh S, Kawai H,Ohta S, Kotake Y*. Methylmercury Decreases AMPA Receptor Subunit GluA2 Levels inCultured Rat Cortical Neurons. Biol Pharm Bull. 2023;46(2):292-300.

総説

佐能 正剛, ヒト肝細胞キメラマウスを用いてヒトにおける薬物性肝障害をどこまで予測できるのか？～さらなる予測性向上を目指して～，谷本学校 毒性質問箱，2023;25

受賞

■2023年3月　2022 Highly Cited Article Award for Biological and Pharmaceutical Bulletin (日本薬学会)

Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures.Yuichi Yokoyama, Yoshifumi Sasaki, Natsuko Terasaki, Taku Kawataki, Koji Takekawa, Yumiko Iwase, Toshinobu Shimizu, Seigo Sanoh,and Shigeru Ohta, Vol. 41, No. 5, pp. 722-732, 2018

＜2022年＞

原著論文

■Tayama Y*, Sugihara K, Sanoh S, Miyake K, Kitamura S, Ohta S. Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats. J Pharm Health Care Sci. 2022; 8(1):31.

■Mizutare T*, Sanoh S*, Kanazu T, Ohta S , Kotake Y. Improved predictability of hepatic clearance with optimal pH for acyl-glucuronidation in liver microsomes. J Pharm Sci. 2022; 111(11): 3165-3173.

■Umeda-Miyara K, Miyara M, Sanoh S, Kotake Y*.Trehalose decreasesmRNA and protein expressions of c-Jun and JunB in human cervical cancer HeLa cells. J Biochem. 2022; 172(3): 177-187.

■Sato K*, Sanoh S*, Ishida Y, Tateno C, Ohta S , Kotake Y. Assessment of metabolic activation of felbamate in chimeric mice with humanized liver in combination with in vitro metabolic assays. J Toxicol Sci. 2022;47(7):277-288.

■Takaoka N , Sanoh S*, Ohta S , Esmaeeli M, Leimkühler S, Kurosaki M, Terao M, Garattini E, Kotake Y, Involvement of aldehyde oxidase in the metabolism of aromatic and aliphatic aldehyde-odorants in the mouse olfactory epithelium, Arch Biochem Biophys, 2022; 715:109099.

■Yoshida K*, Doi Y, Iwazaki N, Yasuhara H, Ikenaga Y, Shimizu H, Nakada T, Watanabe T, Tateno C, Sanoh S , Kotake Y. Prediction of human pharmacokinetics for low-clearance compounds using pharmacokinetic data from chimeric mice with humanized livers. Clin Transl Sci, 2022; 15(1):79-91.

トピックス?その他

■ 高岡 尚輝* , うま味が肥満やメタボリックシンドロームを引き起こすメカニズムの解明, 日本薬学会ファルマシア, 2022年, 58巻(5), 474ページ

受賞

■2022年3月　太田 茂，2022年度 教育賞（日本薬学会）

■2022年2月　佐能 正剛，篮球比分直播3年度 和歌山県立医科大学次世代リーダー賞（和歌山県立医科大学）

＜2021年＞

原著論文

■Motonaga M, Watanabe H, Tayama Y, Shimizu R, Sanoh S, Kotake Y, Kitamura S, Ohta S , Sugihara K*. Comparison of the Components of Three Types of Miso (Fermented Soybean Paste) by 1H NMR Metabolomic Analysis, BPB reports, 2021;4(5):148-154.

■Takada N, Nakamura Y*, Ikeda K, Takaoka N , Hisaoka-Nakashima K, Sanoh S , Kotake Y, Nakata Y, Morioka N*. Treatment with Histone Deacetylase Inhibitor Attenuates Peripheral Inflammation-Induced Cognitive Dysfunction and Microglial Activation: The Effect of SAHA as a Peripheral HDAC Inhibitor. Neurochem Res, 2021;46(9):2285-2296.

■Yabuki A, Miyara M, Umeda-Miyara K, Takao S, Sanoh S , Kotake Y*. MiT/TFE family members supress L-leucyl-L-leucine methyl ester-induced cell death. J. Toxicol. Sci., 46(3), 143-156, 2021.

総説

■Fujino C*, Sanoh S, Katsura T, Variation in expression of cytochrome P450 3A isoforms and toxicological effects: Endo- and exogenous substances as regulatory factors and substrates. Biol Pharm Bull, 2021; 44(11): 1617-1634.

その他

■Sanoh S*, Saito K. Omics analyses and their application for the discovery of biomarkers reflecting drug efficacy and adverse reaction. Drug Metab Pharmacokinet, 2021;39:100405.

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